Preparation of Optically Active N-Carbamylaspartic Acid.
نویسندگان
چکیده
منابع مشابه
Synthesis of Optically Active beta-Amino Acid N-Carboxyanhydrides.
Methodology has been developed for the general synthesis of optically active beta-amino acid N-carboxyanhydrides (beta-NCAs) through cyclization of N(beta)-Boc or N(beta)-Cbz beta-amino acids using phosphorus tribromide. The formation of beta-NCAs was confirmed by spectroscopy as well as an X-ray structural determination of beta-homoalanine-N-carboxyanhydride. The beta-NCA molecules could be po...
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An attempt was made to use a simple procedure to obtain (R)- and (S)-2-aminobutanoic acids [(R)- and (S)-1] which are non-proteinogenic alpha-amino acids and are useful as chiral reagents in asymmetric syntheses. Compound (RS)-1 p-toluenesulfonate [(RS)-2], which is known to exist as a conglomerate, was optically resolved by replacing crystallization with (R)- and (S)-methionine p-toluenesulfon...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1967
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.15.1604